Yeast based expression technology

Our in-house technical support includes integrated teams responsible for:

• Molecular biology manipulation of yeast and protein engineering
• Fermentation
• Process development
• Analytics

We encourage our scientist to take an entrepreneurial approach to customer relationships and we aim to provide a level of technical support that will surpass our clients' expectations.

Our R&D team has developed a series of Saccharomyces cerevisiae strains with various desirable traits including genetic stability, high copy number expression plasmids, protease deficient mutants and strains deficient in the enzymes involved in o-linked glycosylation.

The system is optimized for the production of recombinant proteins where glycosylation does not naturally occur or can be designed out without impacting product efficacy.

We can overcome many of the problems associated with prokaryotic alternatives such as improper disulfide bond assigment, risks of protease degradation and inclusion body formation.  Success in producing difficult to express proteins such as fully functional transferrin further shows the utility of our strains.